Induction of IgA Immune Responses in Nasal Mucosa by Intranasal Immunization of BALB/c Mice
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منابع مشابه
Induction. of IgA Immune Responses in Nasal Mucosa by Intranasal Immunization of BALB/c Mice
Mice were immunized intranasally, orally, intratracheally, or intraperitoneally with outer membrane proteins (OMP) of Haemophilus influenzae and cholera toxin (CT), and Thl/Th2 and B cell immune responses were compared to investigate the mechanisms of mucosal immune responses in the nose and the usefulness of Intranasal immunization for inducing OMP-specific IgA responses. A combined vaccine of...
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15 صفحه اولInduction of specific immunoglobulin A and Th2 immune responses to P6 outer membrane protein of nontypeable Haemophilus influenzae in middle ear mucosa by intranasal immunization.
Nontypeable Haemophilus influenzae (NTHI) is a major pathogen of otitis media. One of the outer membrane proteins of NTHI, P6, is an antigen common to all strains and is considered as a candidate for mucosal vaccine. To elucidate the possibility of developing a nasal vaccine against nontypeable Haemophilus influenzae (NTHI) and to investigate mucosal immune responses in the middle ear, mice wer...
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ژورنال
عنوان ژورنال: Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology)
سال: 1997
ISSN: 0910-9153,1883-7077
DOI: 10.7248/jjrhi1982.36.2_117